Сава Драгунчев има активни регистрации в поне три други мрежи за гей контакти, които ползва/обслужва ежедневно в работно време
Шефът на Национален фонд „Култура“ Сава Драгунчев се подвизава с профил „Кралицата“ в една от популярните гей мрежи за поръчков екстремен секс. Това разкри фотографът Виктор Димчев в профила си във фейсбук.
„Това е шефът на НФК. Това е човекът, който харчи парите за култура на страната. Профилът му в една от популярните гей мрежи за поръчков екстремен секс е „Кралицата“. Има активни регистрации в поне три други мрежи за гей контакти, които ползва/обслужва ежедневно в работно време.
Много мила девойка, по сведения на информатори. Да си знаете кой разпределя порциите в културата след „промяната“. В сравнение Ахмед Доган ми изглежда като небесен ангел. Само за последната година, „Кралицата“ е раздал на гей дружинки повече от 2 млн. лева. За „култура“, пише Виктор Димчев.
Според отчета на фонд „Култура“, публикуван през март тази година, държавно финансиране е получил проект, част от който е шоу с бинго игра, водено от три драг кралици. Програмата е адресирана до посетители на възраст 18+. Сумата в размер на 93 248. 04 лева, е получена от фирмата „Сингъл Степ“ ЕООД, която представлява организацията The Steps.
В бар The Steps, зад която стои „Сингър Степ“ се организират т.нар. партита с драг кралици, в които хомосексуални, травестити, би или транс мъже играят в женски образи. Фондацията е кандидатствала с проект по „Програма за възстановяване и развитие на частни културни организации.”
„Звездното Драг трио, което ще ни забавлява до скъсване и ще ни изпоти от удоволствие са сексапилната пума Пина, горещата Малина и най-свежото и изкусително бижу Емануела!”, така организаторите рекламираха последното драг шоу, проведено на 26 март. Самите организатори изрично уточняват, че проектът е реализиран с подкрепата на Национален фонд „Култура” – това е задължително условие, когато даден проект получи финансиране оттам.
След като гръмна скандалът Министерството на културата начело с Найден Тодоров назначи проверка. Финансирането се извършва по времето на служебния министър на културата Велислав Минеков. Директор на НФК тогава е Мирена Танева, а парите са дадени в мандата на наследника ѝ актьорът ученик на Стефан Данаилов Сава Драгунчев, който заема поста и до сега.
Драгунчев беше сред кандидатите за директор на Народния театър на последния конкурс, спечелен от режисьора Васил Василев. Студентът на Ламбо зае поста и.д. директор на НФК със заповед на скандално известния министър на културата от Продължаваме промяната Атанас Атанасов. Сега стана ясно, че протежето на Просто Наско се подвизава с псевдонима „Кралицата“.
The range of quantification was zero.3 −300 ng ml−1 for each midazolam and 1′-hydroxymidazolam.
The accuracy, within-run and between-run precision were −11.7% ≤ %bias ≤ three.8%, ≤ 8.4% and ≤7.5% for midazolam and −8.3% ≤ %bias ≤ 2.0%, ≤ 9.9% and ≤7.4% for 1′-hydroxymidazolam, respectively.
Plasma concentrations of caffeine and paraxanthine have been decided utilizing
a validated LC-MS/MS technique after strong part extraction. The vary of quantification was
25− ng ml−1 for both caffeine and paraxanthine.
The accuracy, within-run and between-run precision have
been −12.0% ≤ %bias ≤ 10.8%, ≤8.9% and ≤12.0% for caffeine and −13.6% ≤
%bias ≤ eight.0%, ≤6.2% and ≤11.2% for paraxanthine, respectively.
Plasma concentrations of AZD7325 had been determined utilizing a validated LC-MS/MS technique after stable section extraction.
The geometric imply CL/F of caffeine decreased slightly from 5.eight
l h−1 (caffeine alone) to 5.0 l h−1 when given throughout
AZD7325 steady-state administration. The median t1/2
of caffeine alone or co-adminstered with AZD7325 (6.3 vs.
7.zero h) and paraxanthine (7.4 vs. eight.zero h) was related between therapies.
Increase of CYP1A2 activity was noticed in all three preparations of hepatocytes treated with zero.01, zero.1, 1 or
10 µm AZD7325 (Figure 2). The maximal induction response (8.9-fold over automobile controls)
was observed at 1 µm in donor HH210, comparable to fifty four.9% of the adjusted optimistic control β-naphthoflavone
response. In addition, the maximal induction response of 5.1-fold
(17.9% of the constructive control response) and three.1-fold (26.8% of the
optimistic management response) was noticed at 10 µm in donor HH215 and donor HH 216, respectively.
In common, the results from mRNA assays and Western blots have
been according to those noticed from CYP1A2 activity assays.
AZD7325 at 1 or 10 µm caused a maximal CYP1A2 mRNA
expression of three.2-fold, 2.1-fold and a pair of.5-fold in donor HH210, HH215 and HH216, respectively (Figure
3).
Common exercise, significantly power training and high-intensity interval training (HIIT),
can improve testosterone ranges. On the opposite hand, a
sedentary way of life and excessive alcohol consumption can decrease testosterone ranges.
Exposure to certain chemical compounds and pollution, such as pesticides
and plastics, can interfere with hormone manufacturing
and disrupt testosterone ranges. Additionally, chronic stress and lack of sleep can negatively have an effect on testosterone production. High-stress
ranges can increase the production of cortisol, a hormone that may inhibit testosterone production.
Only a qualified doctor in your state can determine if you qualify for and may undertake treatment.
It Is natural for levels to say no with age, however understanding these changes helps in identifying when intervention might be wanted.
Sure genetic variations can affect the production and
metabolism of testosterone, leading to higher or lower ranges in individuals.
The involvement of several totally different methods, including the nervous,
neuroendocrine, vascular and immune techniques, is likely
inevitable (Grounds, 1991; Felten et al. 1993; Ottaway & Husband, 1994; Chambers & McDermott, 1996).
Recommendations have been made that the immune system could play an essential position in adaptation to
bodily stress (Fielding & Evans, 1997), but few studies have yet been performed to directly examine this hypothesis.
One potential rationalization for the shortage of investigations could
be the lack of applicable analytical methods. Some of the methodological
limitations have now been overcome, and quite a few studies
have investigated the impact of exercise on circulating blood leukocytes concerning
absolute number, proportion distribution and in vitro
operate (Pedersen, 1997).
Understanding the conventional and best testosterone levels on your age is
step one towards taking charge of your health and well-being.
Armed with this data, you could make informed selections about how to keep or
improve your hormonal stability, making certain that you just stay energized,
strong, and mentally sharp as you age. A healthcare supplier will evaluate your
symptoms, total health, and particular testosterone ranges to determine if TRT or different interventions are acceptable.
Conditions corresponding to hypogonadism, which is the underproduction of testosterone, can lead to symptoms similar to decreased intercourse drive, fatigue,
and melancholy. Sure drugs, corresponding to
steroids and opioids, can even decrease testosterone levels.
From a medical perspective, each esters are considered protected and effective when used beneath medical supervision. It’s crucial to watch blood work, liver operate, and prostate health throughout therapy.
Moreover, post-cycle remedy (PCT) is often beneficial to help restore
natural testosterone production. Wholesome testosterone ranges depend on numerous components, many of Which Is A Possible Long
Term Effect Of Steroid Use, https://Praca.E-Logistyka.Pl, may be
manipulated by you.
Between 0 and 0.2% (minimum and maximum) of total muscle
space and 0–0.8% of complete epimysium part area expressed CD163.
The share of stained area was similar in all 4 groups and identical to earlier findings in rested human skeletal muscle (Malm et al.
2000). CD11b, the complement 3bi receptor, was detected in 0–0.07%
of the total muscle area and in zero.01–0.80% of the total epimysium section space (Table 5).
The proportion of stained area in muscle was identical to previous findings in rested human skeletal muscle (Malm et al.
2000). It Is necessary to note that hormone ranges
can also be impacted by medical circumstances
and medications.
Chronic stress increases the production of
cortisol, a stress hormone that can inhibit testosterone
manufacturing. Managing stress by way of rest methods, exercise, and healthy coping mechanisms can help keep healthy testosterone levels.
Studies have proven that insufficient sleep or poor sleep high quality can result in decreased testosterone levels.
Lack of sleep disrupts the natural hormonal rhythms, together with testosterone
manufacturing. Therefore, getting enough high-quality sleep is crucial for sustaining optimal testosterone ranges.
Persistent stress has been shown to suppress testosterone manufacturing, resulting in lower levels.
This is as a end result of stress prompts the release of cortisol, a hormone that opposes
the results of testosterone.
9 Comments
The evaluation of structural features was accomplished by computational strategies by method of the type of intermolecular
interactions, crystal energies and Hirshfeld surfaces analysis.
From a pharmaceutical point of view, the solubility of compounds was investigated.
Sufferers using Nebido did report an preliminary qualitative enchancment
of their signs, however because the weeks went on they
observed a dip or trough, with a return of their signs of low testosterone.
This essentially negated the argument for a loading dose with the following
injection interval being twelve weeks. In response, we decreased the interval between the loading dose and the 3rd
dose to 10 weeks for new patients. Injection intervals have been shortened further over
time for our common sufferers till affordable trough levels have been achieved.
Testosterone decanoate’s 15-multi day half-life considers less common dosing and less pinnacles and
box in testosterone ranges. Be that as it may, a quantity of men might favor the more
limited half-existence of cypionate or enanthate to emulate common vacillations higher.
‘s 15-multi day half-life considers less common dosing
and less pinnacles and box in testosterone levels. Mainly,
the same as testosterone enanthate so far as pharmacokinetics,
testosterone cypionate has a considerably longer half-life, ordinarily around 8 to 12 days.
This slight distinction would not basically affect dosing
plans contrasted with enanthate. Dr. Robert Stevens is a UK-trained GP with a special interest in men’s well being and hormone optimisation.
If you could get practically double the milligram amount for a
similar price with enanthate, this is the higher product to go along with palms down.
Amongst the esters examined here, testosterone undecanoate
has the longest half-life, around sixteen to 20 days, and when controlled via intramuscular
infusion, its half-life broadens a lot additional, as lengthy as a while.
This takes into consideration exceptionally uncommon dosing plans, like once every
10 to 14 weeks, making it an incredibly advantageous selection for long haul treatment, but at the expense of less precise command
over testosterone levels. Testosterone (17β-Hydroxyandrost-4-en-3-one) is
the first male anabolic-androgenic steroid. The crystal
structures of two medium and two long esterified forms of
testosterone, including enanthate, cypionate, decanoate and undecanoate, were decided by X-ray single crystal diffraction. The
samples had been also characterized by powder X-ray diffraction, FT-IR spectroscopy and thermal evaluation (DTA, TG).
Crystalline powders of esters for scientific research functions have been acquired from Wuhan Shu Mai Technology Co.
(Wuhan, China), while the solvents were obtained from Merck.
Varied oils of USP grade were received from Sigma-Aldrich
(St. Louis, MO, USA), Tex Lab provide and Med Lab supply (USA).
With the increase in temperature, no thermal events occurred till the onset temperature of 320 °C for long esters (TDec, TUnd)
and as a lot as 350 °C for medium esters (TEna, TCyp).
Clearly with out the use of an ester, maintaining
constant blood ranges with an injectable anabolic/androgen could be far more troublesome.
The half-existence of a testosterone ester is a major perspective to contemplate when it is endorsed for testosterone substitution remedy or utilized in the working out
native area for execution improve. The half-existence of a medication is the time it takes for the centralization of the treatment within the circulatory system to
diminish significantly.
To treat illnesses in hormone healing, two completely different types of the identical best Steroid website current Testosterone Decanoate and Undecanoate medicines.
Nevertheless, their chemical compositions, properties,
and therapeutic functions differ significantly.
In order to properly select an appropriate option, each medical service
specialists and individuals need to understand these disparities.
Testosterone Decanoate is a long-acting ester of
testosterone, which is much of the time utilized in testosterone commerce therapy and for the aim of lifting weights.
While topical utility of testosterone cream or gel remains an inexpensive selection of delivery methodology, there are potential limitations to its efficacy due to inconsistent absorption with the skin barrier.
In my skilled opinion, gold standard TRT is daily subcutaneous injections of Testosterone
Enanthate or Cypionate and HCG, that is something I focus
on in detail in TRT Finest Practice. The aim of Testosterone Replacement Remedy (TRT) is to revive your androgen ranges
to within normal physiological parameters. The aim of Testosterone Optimisation Remedy (TOT) is to optimise your androgen levels so that you feel
the qualitative and quantitative advantages of getting healthy
hormonal ranges.
Medical service specialists can contain individuals in discussions about the advantages and downsides
of different medication choices. It entails contemplating affected person preferences,
lifestyle elements, and treatment objectives when deciding Testosterone Undecanoate vs Decanoate.
Testosterone Undecanoate is a suitable choice for individuals who favor oral administration in order
to bypass injections. Testosterone decanoate may be chosen by those unconcerned with receiving photographs.
Evaluating intake preferences of Testosterone Decanoate
vs Undecanoate, by intramuscular injection the former is usually administrated.
The popularity of medical service specialists may be influenced by their familiarity with numerous hormone formulations and prescribing habits.
More frequent smaller doses are sometimes higher at achieving precise regular levels.
SHBG which binds to testosterone is usually the figuring out consider deciding injection frequency.
It comes as no secret that both subcutaneous and shallow intramuscular injections
are the most effective methodology of delivering a
consistent dose of testosterone to the bloodstream. Subcutaneous
injections have two important advantages over
intramuscular injections, they’re much less painful and the
speed of absorption is slower causing much less aromatisation of testosterone
to oestradiol. While oestrogen is incredibly necessary in cognitive
perform, temper, libido, fertility, cardiovascular health and
maintaining bone power, an extreme quantity of is as dangerous as too little.
Der größere Teil ist an Albumin (33 %) und SHBG (65 %) gebunden. Das freie Testosteron kann nach der Bestimmung des Gesamttestosterons, des SHBGs und
des Albumins durch die Vermeulen-Formel berechnet werden. Im klinischen Alltag wird das freie Testosteron im Blut oft durch den freien Androgenindex abgebildet.
Wie bei anderen Steroidhormonen geht die Biosynthese des Testosterons von Cholesterin aus.
Aus meinem Freundeskreis masturbiert jede4 junge vielleicht 10 mal Pro Contra Testosteron Therapie Woche.
Denn wie schon erwähnt, können plötzlich unvermutet doch noch Barthaare
aus den Poren wachsen. Bist du etwas älter, kannst du dir
Barthaare bei einem spezialisierten Mediziner implantieren lassen. Mit Push-up-BHs,
aufgeklebten Wimpern und aufgestecktem Kunsthaar zaubern sie sich fürs Date Holz
vor die Hütte, einen Engelsblick und Löwenmähne herbei.
Fehlt dir jedoch nur besagtes Testosteron, so kann dir der Arzt das
verabreichen oder du könntest ein entsprechendes hormonhaltiges
Bartwuchsprodukt nehmen.
Die eher selten auftretenden Tumore der Keimdrüsen in den Eierstöcken befallen meist jüngere Frauen. Obwohl diese Tumore überwiegend gutartig sind, gehen sie mit höheren Testosteron einher.
Extrem überhöhte Werte finden sich in der Regel beim Zuführen in schädlichem Maß, um die eigene
Leistung steigern zu wollen. Zu viel Testosteron im Kreislauf kann zu einer niedrigen Frustrationstoleranz
führen, bis hin zu aggressivem Verhalten. Zu hoher Blutdruck kann
ebenso zu einer unerwünschten Begleiterscheinung eines zu hohen Testosteronspiegels werden. Eine hohe Konzentration im Blut verursacht Testosteron Nebenwirkungen. So bekommt ein Kraftsportler
neben stärkerer Muskulatur auftretende Hautprobleme, wie Pickel.
Dieser Methode liegt ein ähnliches Prinzip, wie der Geltherapie zugrunde.
Das Pflaster wird auf eine bestimmte Körperstelle geklebt, beispielsweise auf den Rücken, die Oberarme oder den Bauch,
und setzt seine Wirkung über die Haut frei. Hier geht
die Freisetzung ebenfalls relativ gleichmäßig vonstatten, allerdings sind die Pflaster
aufgrund ihrer immensen Nebenwirkungen (vor allem starke Hautirritationen) kaum
noch erhältlich. Vor allem im letzten Lebensdrittel hat
der Mann mit einem fallenden Testosteronspiegel zu kämpfen. Zu den Folgen gehören Libidoverlust, Erektionsstörungen, Gewichtszunahme und Energieverlust.
Wenn Sie dabei Druck auf die vordere Scheidenwand ausüben,
stimulieren Sie den sogenannten G-Punkt, der für besonders intensive vaginale Orgasmen verantwortlich
sein soll. Seine Existenz ist allerdings unter Wissenschaftlern umstritten. Um zum Orgasmus zu
kommen, stimulieren viele Frauen zusätzlich zur Scheidenpenetration Klitoris und Vulva.
Um lustvoll zu masturbieren, braucht man vor allem Zeit und Ruhe.
Am besten suchen Sie sich ein stilles, kuscheliges Plätzchen, an dem Sie sicher sein können, nicht gestört zu werden. Für eine entspannte Stimmung können Kerzenlicht und leise Musik sorgen.
Stress, Gesundheit, Beziehungsstatus, Zeit und viele andere Faktoren können die Häufigkeit des Masturbierens beeinflussen. Sowohl tägliches Masturbieren als auch weniger häufiges Masturbieren können völlig
gesund sein. In solchen Fällen können Betroffene den Eindruck haben,
dass Masturbieren schädlich ist. Es ist jedoch nicht die Masturbation an sich, die schädlich ist,
sondern das Ausmaß und der Kontext, in dem sie betrieben wird.
Es wird in den Leydigschen Zwischenzellen des Hodens,
im Ovar und in der Nebennierenrinde produziert.
Diese Unterscheidung erklärt auch das Phänomen, warum manche Männer mit einem “normalen” Testosteronspiegel die Symptome eines
Testosteronmangels erfahren können. Selbst als ich für knapp 2 Jahre an einem Testosteronmangel litt,
riet mir mein Arzt von der Einnahme ab. Die Ursache darin liegt meist in einer Dysbalance zwischen dem männlichen Testosteron und dem weiblichen Östrogen. Von 100 übergewichtigen Männern bekam die Hälfte Testosteron verabreicht, die andere Hälfte ein Placebo.
Bei der Diagnose eines niedrigen Testosteronspiegels
berücksichtigen die Ärzte auch die Symptome.
Stressfaktoren lassen sich leider nie vollständig vermeiden. Die Lösung für härtere Erektionen ist daher den Umgang mit Stress zu meistern. Letzteres führt dazu, dass du immer größere
sexuelle Reize benötigst, um noch gleich erregt zu werden.